No. 1 seed Auburn Tigers basketball First Round 2025 NCAAA Tournament in Lexington, Ky. (AP … [+] Photo/James Crisp)

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The First Round of the 2025 NCAA Tournament is producing major watch and wager action across the U.S. As the games play out and leading online sportsbooks take more bets, the betting lines and odds adjust. Many moved quickly in the opening round games Thursday and Friday, and now the Round of 32 (second round) matchups are being posted along with betting odds as the Thursday games are completed.

As bettors craft their bets for Friday’s college basketball games, those completed contests and the next Round of 32 matchups and odds with be added and updated below.

March Madness Matchups And Odds Round Of 32

FanDuel Sportsbook provides college basketball betting odds and futures, which refresh periodically and are subject to change, including on props and live betting. Bet types, odds and betting terms along with upcoming games and odds will be updated as provided by FanDuel and leading online sportsbooks. Betting favorites (-) listed along with game total.

Sat., March 22

Midwest

• No. 12 McNeese vs. No. 4 Purdue (-6.5), 142.5
• No. 8 Gonzaga vs. No. 1 Houston (-4.5), 139.5
• No. 7 UCLA vs. No. 2 Tennessee (-4.5), 132.5

East

• No. 6 BYU vs. No. 3 Wisconsin (-1.5), 154.5

West

• No. 10 Arkansas vs. No. 2 St. John’s (-6.5), 143.5
• No. 11 Drake vs. No. 3 Texas Tech (-7.5), 126.5

South

• No. 5 Michigan vs. No. 4 Texas A&M (-1.5), 140.5
• No. 9 Creighton vs. No. 1 Auburn (-8.5), 150.5

Betting Stats And Trends

• Under coach Mark Few, Gonzaga is 0-9 straight up (SU) and 1-8 against the spread (ATS) vs. No. 1 seeds, per the Playbook Newsletter.
• Second round Top 4 seeds that won but didn’t cover the spread in the first round are 44-17 SU and 33-27-1 ATS (55%) since 2013.
• They are also 34-24-3 Under (58.6%) the total, per the VSiN research team (Auburn, Tennessee, Texas Tech)

As you bet on March Madness and review the matchups and odds, know you can transform your brackets and bets on FanDuel with additional ways to wager on the games. The multi-round parlay feature is a new popular betting option and provides basketball fans and FanDuel customers more flexibility as they make their picks and bets during March Madness.

Sunday, March 23

Midwest

East

West

South

You can be on it.

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