The second-seeded and defending NBA champion Boston Celtics will look to take a commanding lead in the series when they battle the seventh-seeded Orlando Magic in Game 2 of their Eastern Conference first-round matchup on Wednesday. Boston rolled to a 103-86 win in Game 1 on Sunday, as Boston shut down Orlando’s role players as no one besides Paolo Banchero or Franz Wagner scored more than seven points. The Magic (41-41), who have won five of their last seven games, are 19-23 on the road in 2025. The Celtics (61-21), who have a plus-9.1 point differential this season, are 29-13 on their home court. Small forward Jayson Tatum (wrist) is doubtful for the game.

Tip-off from TD Garden in Boston is set for 7 p.m. ET. Orlando won two of three matchups in the regular season. The Celtics are 10.5-point favorites in the latest Magic vs. Celtics odds from DraftKings sportsbook, after the game opened with Boston favored by 14 points. The over/under for total points scored is 196.5. The Celtics are -538 on the money line (risk $538 to win $100), while the Magic are +397 (risk $100 to win $397).

Before making any Magic vs. Celtics picks, check out the NBA predictions from the SportsLine Projection Model.

The SportsLine Projection Model simulates every NBA game 10,000 times and has returned well over $10,000 in profit for $100 players on its top-rated NBA picks over the past six-plus seasons. The model enters the first full week of the 2025 NBA playoffs on a sizzling 156-116 roll on all top-rated NBA picks dating back to last season, returning nearly $4,000. It is also 22-11 (67%) on top-rated NBA against-the-spread picks this season. Anyone following could have seen HUGE returns!

The model has simulated Magic vs. Celtics 10,000 times and the results are in. We can tell you that the model is leaning Over on the point total, and it also says one side of the spread hits well over 60% of the time!