The Emmy Award-winning Fox TV show premiered in 2000 and ended in 2006, after seven seasons.

The single-camera comedy series followed the dysfunctional working-class family of child prodigy Malcolm, who was often seen making asides to the camera to comment on their failures.

The musically-gifted Dewey often fell victim to his brothers’ pranks and developed a high tolerance for pain, often scheming to get one up on his brothers and parents.

Due to a misunderstanding at school, Dewey was placed in a class well below his intelligence and, as a result, served as their self-appointed teacher.

After the birth of their youngest brother Jamie, Dewey became the first to break the cycle of tormenting the baby of the family.

The sitcom, often listed as a modern classic of the genre, is set to begin production once more in Vancouver, Canada, in the coming weeks.

Malcolm now has a teenage daughter – portrayed by Keeley Karsten – and the synopsis for episode one says the pair will get “drawn into the family’s chaos when Hal and Lois demand his presence for their 40th wedding anniversary party”.

Christopher Masterson, who played Malcolm’s oldest brother Francis, and Justin Berfield, who played Reese, will also both return for the reboot, according to Variety, while Kiana Madeira will join the show afresh as the eponymous star’s girlfriend.

Also, Riverdale actor Anthony Timpano will play Jamie, and Vaughan Murrae will feature as his youngest sibling, Kelly.