If we’re in a post- “John Wick” era, where action cinema has been revitalized and modernized — more bullets and blood, more choreographed spectacle — the thrills of the genre have strangely edged closer and closer to that earliest of movie pleasures: slapstick. Particularly in the man-on-a-rampage subgenre, as the violence and gore becomes increasingly absurd, these movies begin to echo that old format, where the more creative and outrageous the pain, the more visceral the pleasure.

That’s essentially the kind of silly, gross-out fun of “Novocaine,” which taps into this understanding about as overtly as possible. The key is in the invincibility clause — if, like the Three Stooges themselves, our action hero is virtually indestructible, the pain and its wacky payoffs can be endless.

Other films have presented unique and often inane spins on this idea (from Jason Statham in “Crank” to Logan Marshall-Green in “Upgrade”), but this film, directed by Robert Olsen and Dan Berk, takes it to its most extreme, via an almost stupidly simple premise: Because of a genetic disorder, our protagonist Nate Caine (Jack Quaid) can’t feel any physical pain. Cue just about as many ways one can try to invoke it.

Nate, though, is no willing bionic man, but in fact the opposite. Because he doesn’t have the sensors of pain to notify him if something has gone wrong, he’s led a conversely bubble-boy existence, fearful that at any moment he might unknowingly injure and kill himself. He tennis-balls the corners of desks, doesn’t eat solid foods (God forbid he bites off his own tongue!) and has become a bit of a recluse.

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